Extensive data proves benefits of titanised mesh implants
Leading evidence-based medicine: Providing verifiably effective solutions and products - this is our lived vision. Over the years, pfmmedical has collected a large amount of data pertaining to the use and benefits of titanised meshes, in line with the company claim "Quality and Experience". We have summarized all of these studies on our website.
First of all, the benefits of titanized meshes at a glance:
- Titanised polypropylene mesh is an innovative bioactive material that fully integrates and heals normally1 (study abstract of Gentile et al.)
- Titanisation reduces the inflammatory response2, leads to less scarring3 and thus reduces mesh shrinkage3,4,5. Find out more about the benefits of titanisation here.
When it comes to titanised meshes, pfmmedical has extensive expertise. Our experience with titanised meshes in figures:
- 21 years of meshes for hernias (since 2002, more than 500,000 meshes)
- 15 years of meshes for breasts (since 2008, more than 100,000 meshes)
- 17 years of meshes for the pelvic floor (since 2006, more than 100,000 meshes)
More important than this purely quantitative experience, are our qualitative study results. Here you will fina a large number of studies sponsored by pfmmedical which in particular reflect pfmmedical's sense of responsibility towards users and patients:
In this context, we would also like to explicitly refer once again to the Herniamed Registry, a quality assurance study (https://www.herniamed.de/). That it is important and makes a valuable contribution was proven by the Herniamed Registry in 2016 when it helped uncover the increased recurrence rate with the use of the Ethicon Physiomesh™, resulting in this mesh being withdrawn from the market in 2016.6 The Herniamed registry shows no abnormalities with titanised meshes.
By the way - our titanised meshes for breast surgery have been CE-certified since 2021, a certification granted on the basis of the available data in accordance with the Medical Devices Regulation (EU) 2017/745. With this early certification date, we are sending a clear signal for high-quality products with proven benefits - all with the ‘Made in Germany’ quality mark as well.
1 Gentile et al., Bioact Mater. 2021 May 19;6(12):4640-4653. doi: 10.1016/j.bioactmat.2021.05.002
2 Scheidbach et al., Surg Endosc. 2004 Feb;18(2):211-20. doi: 10.1007/s00464-003-8113-1
3 Scheidbach et al., Eur Surg Res. 2004 Sep-Oct;36(5):313-7. doi: 10.1159/000079917
4 Zhu et al., World J Gastrointest Surg. 2015 Oct 27;7(10):226-36. doi: 10.4240/wjgs.v7.i10.226
5 Wood et al., J Mater Sci Mater Med. 2013 Apr;24(4):1113-22. doi: 10.1007/s10856-013-4872-y.
6 Pawlak et al., Surg Endosc. 2016 Mar;30(3):1188-97. doi: 10.1007/s00464-015-4329-0